- Created Cardinal:
- Robert Francis Prevost, O.S.A., Prefect of the Dicastery for Bishops; Age: 68.0; Cardinal-Deacon of Santa Monica
- Claudio Gugerotti, Prefect of the Dicastery for the Eastern Churches; Age: 67.9; Cardinal-Deacon of Sant’Ambrogio della Massima
- Victor Manuel Fernández, Prefect of the Dicastery for the Doctrine of the Faith; Age: 61.1; Cardinal-Deacon of Santi Urbano e Lorenzo a Prima Porta
- Emil Paul Tscherrig, Apostolic Nuncio to Italy; Age: 76.6; Cardinal-Deacon of San Giuseppe in via Trionfale
- Christophe Louis Yves Georges Pierre, Apostolic Nuncio to United States of America; Age: 77.6; Cardinal-Deacon of San Benedetto fuori Porta San Paolo
- Pierbattista Pizzaballa, O.F.M., Patriarch of Jerusalem {Gerusalemme}, Palestine; Age: 58.4; Cardinal-Priest of Sant’Onofrio
- Stephen Brislin, Archbishop of Cape Town {Kaapstad}, South Africa; Age: 67.0; Cardinal-Priest of Santa Maria Domenica Mazzarello
- Ángel Sixto Rossi, S.J., Archbishop of Córdoba, Argentina; Age: 65.1; Cardinal-Priest of Santa Bernadette Soubirous
- Luis José Rueda Aparicio, Archbishop of Bogotá, Colombia; Age: 61.5; Cardinal-Priest of San Luca a Via Prenestina
- Grzegorz Ryś, Archbishop of Łódź, Poland; Age: 59.6; Cardinal-Priest of Ss. Cirillo e Metodio
- Stephen Ameyu Martin Mulla, Archbishop of Juba, South Sudan; Age: 59.7; Cardinal-Priest of Santi Gemma Galgani
- José Cobo Cano, Archbishop of Madrid, Spain; Age: 58.0; Cardinal-Priest of Santa Maria in Monserrato degli Spagnoli
- Protase Rugambwa, Coadjutor Archbishop of Tabora, Tanzania; Age: 63.3; Cardinal-Priest of Santa Maria in Montesanto
- Sebastian Francis, Bishop of Penang, Malaysia; Age: 71.8; Cardinal-Priest of Santa Maria Causa Nostrae Laetitiae
- Stephen Chow Sau-yan, S.J., Bishop of Hong Kong [Xianggang], China; Age: 64.1; Cardinal-Priest of San Giovanni Battista de La Salle
- François-Xavier Bustillo, O.F.M. Conv., Bishop of Ajaccio, France; Age: 54.8; Cardinal-Priest of Santa Maria Immacolata di Lourdes a Boccea
- Américo Manuel Alves Aguiar, Bishop of Setúbal, Portugal; Age: 49.7; Cardinal-Priest of Sant’Antonio da Padova in Via Merulana
- Ángel Fernández Artime, S.D.B., Rector General of Salesians of Saint John Bosco; Age: 63.1; Cardinal-Deacon of Santa Maria Auxiliatrice in via Tuscolana
Count: 18; Average Age: 63.7 - Created Cardinal (Non-Voting):Count: 3; Average Age: 87.9
